CLAMYCIN ™
CLAMYCIN 500 TABLET | |
---|---|
Generic : | Clarithromycin |
Thearapeutic : | Antibiotics |
Pack Size : | 15s |
Strength : | 500 mg |
Dosage Form : | Tablet |
Clamycin
Clarithromycin USP
DESCRIPTION
Clamycin (Clarithromycin) is an antibiotic of the macrolide family and is a semisynthetic derivative of erythromycin. Clamycin (Clarithromycin) is rapidly absorbed from the gastrointestinal tract. It exerts its antibacterial action by binding to the 50S ribosomal subunit of susceptible bacteria and suppresses protein synthesis. It is highly effective against a wide variety of aerobic and anaerobic gram-positive and gram-negative organisms.
COMPOSITION
- Clamycin 500 mg Tablet: Each film-coated tablet contains Clarithromycin USP 500 mg.
INDICATIONS
- Lower respiratory tract infections: Acute and chronic bronchitis, pneumonia.
- Upper respiratory tract infections: Sinusitis, pharyngitis, acute and chronic otitis media.
- Skin and soft tissue infections of mild to moderate severity and other infections caused by susceptible microorganisms.
- Clamycin is also indicated as an adjunct in the treatment of duodenal ulcers for the eradication of H. pylori.
- Disseminated or localized mycobacterial infections due to Mycobacterium avium or Mycobacterium intracellular. Localized infections due to Mycobacterium chelonae, Mycobacterium fortuitum, or Mycobacterium kansasii.
DOSAGE AND ADMINISTRATION
Adults :
The recommended dosage in adults is 250 mg every 12 hours for 7 days. In severe cases, dosage may be increased up to 500 mg every 12 hours for up to 14 days. Eradication of H. pylori Clamycin 500 mg thrice daily with Omeprazole 40 mg once daily followed by Omeprazole 20 mg once daily (2 weeks regimen). Amoxycillin or Tetracycline is to be added to the above regimen as per the suggestion of The American College of Gastroenterology. Or Omeprazole 20 mg twice daily, Clamycin 500 mg twice daily, and Amoxycillin 1 g twice daily (1 week regimen).
Children :
- The normal daily dose for children aged 6 months and above is 15 mg per kg of weight, taking half the daily dose in the morning and the other half in the evening.
Patients with renal failure and liver disease :
- A dose reduction of Clarithromycin is recommended for patients with creatine clearance rates of <30ml per minute. Dosage adjustment is not necessary for patients with impaired hepatic function. Food does not influence the absorption of it. The duration of treatment is 7-10 days.
OR AS DIRECTED BY THE PHYSICIAN.
SIDE EFFECTS
Clarithromycin is generally well tolerated. Side effects include nausea, vomiting, diarrhea, and abdominal pain. Stomatitis and glossitis have been reported. Other side effects include headaches and allergic reactions ranging from urticaria and mild skin rashes.
CONTRAINDICATIONS
- It is contraindicated in patients with known hypersensitivity to Clarithromycin or any other macrolide antibiotics.
PRECAUTIONS
Clarithromycin is principally excreted by the liver and kidney. Caution should be exercised in administering this antibiotic to patients with impaired hepatic and renal functions. Prolonged or repeated use of Clarithromycin may result in an overgrowth of non-susceptible bacteria or fungi. If superinfection occurs, Clarithromycin should be discontinued and appropriate therapy instituted. Concomitant administration with Theophylline has been associated with increased serum Theophylline levels. Effects of Digoxin and Warfarin may be potentiated with concomitant administration with Clarithromycin.
DRUG INTERACTIONS
- Clarithromycin should not be prescribed with Terfenadine and Cisapride.
Storage
- Store below 300C & dry place, protected from light. Keep out of reach of children.
Commercial Pack
- Clamycin 500 mg Tablet: Each box contains 3 x 4 tablets in an Alu blister pack.
Biopharma Ltd. produces CLAMYCIN 500 TABLET, It is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.