Biocin

Chlorphenamine maleate

COMPOSITION

• Biocin 4 mg Tablet: Each tablet contains 4 milligrams of chlorphenamine maleate
• Biocin 100 ml Syrup: Each 5 ml syrup contains Chlorpheniramine Maleate BP 2 mg.

THERAPEUTIC INDICATIONS

• Biocin tablets are indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic edema, food allergy, drug and serum reactions, and insect bites.
• Also indicated for the symptomatic relief of itch associated with chickenpox.

DOSAGE AND ADMINISTRATION

• Oral Administration only
• Do not exceed the stated dose or frequency of dosing
• Adults and children 12 years and over 1 tablet 4 to 6 hourly. Maximum daily dose: 6 tablets (24 mg) in any 24 hours
• Elderly: The elderly are more likely to experience neurological anticholinergic effects. Consideration should be given to using a lower daily dose (e.g. a maximum of 12 mg in any 24 hours).
• Children aged 6 - 12 years: ½ tablet 4 to 6 hourly. Maximum daily dose: 3 tablets (12mg) in any 24 hours.
• Upto 1 Year: ½ Teaspoonful 2 times daily
• 1-5 years: ½-1 Teaspoonful 2 times daily

CONTRAINDICATIONS

• Biocin tablets are contra-indicated in patients who are hypersensitive to antihistamines or to any of the tablet ingredients.
• The anticholinergic properties of chlorphenamine are intensified by monoamine oxidase inhibitors (MAOIs). Biocin Tablets are therefore contra-indicated in patients who have been treated with MAOIs within the last fourteen days.

PREGNANCY AND LACTATION

Pregnancy: There is no adequate data on the use of chlorphenamine maleate in pregnant women. The potential risk for humans is unknown. Use during the third trimester may result in reactions in the newborn or premature neonates. Not to be used during pregnancy unless considered essentially by a physician.

Lactation: Chlorphenamine maleate and another antihistamine may inhibit lactation and may be secreted in breast milk. Not to be used during lactation unless considered essential by a physician

SIDE EFFECT

Specific estimation of the frequency of adverse events for OTC products is inherently difficult (particularly numerator data). Adverse reactions that have been observed in clinical trials and which are considered to be common (occurring in? 1% to <10% of subjects) or very common (occurring in ?10% of subjects) are listed below by MedDRA System Organ Class. The frequency of other adverse reactions identified during post-marketing use is unknown.

OVERDOSE

The estimated lethal dose of chlorphenamine is 25 to 50mg/kg body weight. Symptoms and signs include sedation, paradoxical excitation of the CNS, toxic psychosis, convulsions, apnoea, anticholinergic effects, dystonic reactions, and cardiovascular collapse including arrhythmias.

Biopharma Ltd. produces BIOVIT GOLD 30S TABLET, It is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.