Bacron

Mupirocin

PRESENTATION

• Bacron Ointment 10 gm: Each gram of ointment contains Mupirocin BP 20 mg.

INDICATIONS

• Mupirocin ointment (Bacron ointment) 2% is indicated for the topical treatment of impetigo due to Staphylococcus aureus, beta-hemolytic Streptococcus, and Streptococcus pyogenes.

DOSAGE AND ADMINISTRATION

A small amount of Mupirocin ointment (Bacron ointment) 2% should be applied to the affected area three times daily for up to 10 days. The area treated may be covered with gauze dressing if desired. Patients not showing a clinical response within 3 to 5 days should be re-evaluated

CONTRA-INDICATIONS

• Mupirocin ointment is contraindicated in patients with a history of hypersensitivity reaction to Mupirocin

WARNING

• Mupirocin ointment is not for ophthalmic use, so care should be taken during use on the face.

PRECAUTIONS

If a hypersensitivity reaction or chemical irritation should occur with the use of Mupirocin ointment, treatment should be discontinued and appropriate alternative therapy for the infection instituted. As with other antibacterial products, prolonged use may result in the overgrowth of non-susceptible organisms, including fungi. Mupirocin ointment is not formulated for use on mucosal surfaces. Intranasal use has been associated with isolated reports of stinging pain and drying polyethylene glycol can be absorbed from open wounds and damaged skin and is execrated by the kidneys. In common with other polyethylene glycol-based ointments. Mupirocin ointment should not be used in conditions where absorption of large quantities of polyethylene glycol is possible, especially if there is evidence of moderate or severe renal impairment.

USE IN PREGNANCY AND LACTATION

Reproduction studies have been performed in rats and rabbits at systemic doses, i.e. orally, subcutaneously, and intramuscularly up to 100 times the human topical dose, and have revealed no evidence of impaired fertility or harm to the fetus due to Mupirocin. There are however no adequate and well-controlled studies in pregnant women, Because animal studies are not always predictive of human response. Mupirocin should be used during pregnancy only if clearly needed. It is not known whether this drug is excreted in human milk Because many drugs are excreted in human milk. Caution should be exercised when Mupirocin ointment is given to nursing.

USE IN PEDIATRIC PATIENT

The safety and effectiveness of Mupirocin ointment have been established in the age range of 2 months to 16 years. The use of Mupirocin ointment in these age groups is supported by evidence from adequate and well-controlled studies.

SIDE EFFECTS

Burning, stinging, or pain in 15% of patients, itching in 1% of patients, rash, nausea, erythema, dry skin, tenderness, contact dermatitis, and increased exudates in less than 1% of patients, Systemic reactions to Mupirocin ointment have occurred rarely.

PHARMACEUTICAL PRECAUTIONS

• Store in a cool and dry place, and protect from light.

COMMERCIAL PACK

• Bacron ointment 10 gm: Each tube contains 10 gm Ointment.

Biopharma Ltd. produces BACRON 10 GM OINTMENT, It is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.