TOP ™

TOP 100 MG TABLET
Generic : Ketoprofen
Thearapeutic : NSAIDs
Pack Size : 30s
Strength :
Dosage Form : Tablet

Top

Ketoprofen

Presentation:

  • Top 50 mg Tablet: Each enteric-coated tablet contains Ketoprofen BP 50 mg.
  • Top 100 mg Tablet: Each enteric-coated tablet contains Ketoprofen BP 100 mg.

Description

with analgesic and anti-pyretic action. The anti-inflammatory activity is greater than that of aspirin.

Indications

1. Rheumatic disease anti-inflammatory and analgesic use in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and gout.

2. Periarticular and musculoskeletal indications for analgesia in bursitis, tendinitis, synovitis, tenosynovitis, and lumbago.

3. Prophylaxis and treatment in migraine headaches.

4. Surgical and traumatic uses analgesic action after sports injuries, orthopedic manipulation, dental extraction, etc.

5. Infectious disease-for anti-inflammatory, analgesic, and antipyretic purposes.

6. Gynaecological uses-in dysmenorrhoea, following intrauterine contraceptive device insertion and analgesia in the postpartum, non-nursing mother.

Dosage & administration

Adults: 50 to 100 mg every 4 hours, repeated up to a maximum of 200 mg in 24 hours. Following a satisfactory response oral therapy should be instituted with Ketoprofen tablet. It is recommended that the injection should not normally be continued for longer than 3 days. Elderly: As with other medications it is generally advisable in the elderly to begin Ketoprofen therapy at the lower end of the dose range and to maintain such patients on the lowest effective dosage.

Contraindications

-Active peptic ulceration,

-A history of recurrent peptic ulceration or chronic dyspepsia,

-Severe renal dysfunction,

-Disease in children (safety/dosage during long-term treatment has not been established). -Patients with a known hypersensitivity to ketoprofen or sensitive to aspirin or other non-steroidal anti-inflammatory agents.

-Severe bronchospasm might be precipitated in these patients and in those suffering from or with a history of bronchial asthma or allergic disease.

Drug interaction

Ketoprofen is highly protein-bound. Concomitant use of other protein-binding drugs, e.g. anticoagulants, sulphonamides, and hydantoins might necessitate modification of dosage in order to avoid increased levels of such drugs resulting from competition for plasma protein-binding sites. Similar-acting drugs such as aspirin or other non-steroidal anti-inflammatory agents should not be administered concomitantly with ketoprofen as the potential for adverse reactions is increased. Serious interactions have been recorded after the use of high-dose methotrexate with NSAID including ketoprofen.

Overdosage

Like other propionic acid derivatives, ketoprofen is of low toxicity in overdosage, symptoms after acute ketoprofen intoxication are largely limited to drowsiness, abdominal pain, and vomiting but adverse effects seen after overdosage with propionic acid derivatives such as hypotension, bronchospasm, and gastrointestinal haemorrhage should be anticipated. Treatment is otherwise supportive and symptomatic.

Storage Condition

Store in a cool dry place which protects from heat & light.

Commercial pack

  • Top 50 mg Tablet: Box Containing 5 X 10 Tablets in Alu-PVC Blister pack.
  • Top 100 mg Tablet: Box Containing 3 X 10 Tablets in Alu-PVC Blister pack.

Biopharma Ltd. Produces a TOP 100 MG TABLET it is a trusted product for alleviating various discomforts, commonly found in pharmacies and stores.

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