REVISTAR ™
REVISTAR 500 MG CAPSULE | |
---|---|
Generic : | Flucloxacillin |
Thearapeutic : | Antibiotics |
Pack Size : | 28s |
Strength : | |
Dosage Form : | Capsule |
Revistar
Flucloxacillin
COMPOSITION
- Revistar 250 mg capsule: Each capsule contains Flucloxacillin 250 mg (as Flucloxacillin Sodium BP).
- Revistar 500 mg capsule: Each capsule contains Flucloxacillin 500 mg (as Flucloxacillin Sodium BP).
- Revistar powder for suspension 100 ml: Each 5 ml suspension contains Flucloxacillin 125 mg (as Flucloxacillin Sodium BP).
INDICATIONS
- Flucloxacillin is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by beta-lactamase-producing staphylococci.
Typical indications include:
- Skin and soft tissue infections: Boils, abscesses, carbuncles, furunculosis, cellulitis; infected skin conditions, e.g. ulcer, eczema and acne; infected wounds, infected burns, protection for skin grafts, otitis media and impetigo.
- Respiratory tract infections: Pneumonia, lung abscess, empyema, sinusitis, pharyngitis, tonsillitis and quinsy.
- Other infections caused by Flucloxacillin-sensitive organisms are osteomyelitis, enteritis, endocarditis, urinary tract infections, meningitis, and septicaemia.
- Flucloxacillin is also indicated for use as a prophylactic agent during major surgical procedures where appropriate; for example, cardiothoracic and orthopaedic surgery.
DOSAGE AND ADMINISTRATION
- Oral doses should be administered half to one hour before meals.
- Usual adult dosage (including elderly patients): 250 mg four times daily.
- In severe infections, the dosage should be doubled.
- In osteomyelitis and endocarditis: up to 8 gm daily, in divided doses 6 to 8 hourly.
- In case of secondary bacterial infection in chicken pox: Flucloxacillin 500 mg six hourly should be prescribed.
Usual Children Dosage
- 2-10 years: half of the adult dose.
- Under 2 years: a quarter of the adult dose.
- Dose adjustment in renal impairment: As common with other penicillins, Flucloxacillin usage in patients with renal impairment does not usually require dosage reduction. However, in the presence of severe renal failure (creatinine clearance < 10 ml/min) a reduction in dose or an extension of dose interval should be considered.
- Flucloxacillin is not significantly removed by dialysis and hence no supplementary dosages need to be administered either during or at the end of the dialysis period.
CONTRA-INDICATION
- Penicillin hypersensitivity.
SIDE EFFECTS
- Side effects as with other penicillin, are uncommon and mainly of a mild and transitory nature. Gastrointestinal upsets (e.g. nausea, diarrhoea) and skin rashes have been reported. If skin rash occurs, treatment should be discontinued.
DRUG INTERACTION
- The administration of probenecid with Flucloxacillin results in higher serum peak concentrations and prolongs the time that therapeutic concentrations of Flucloxacillin are achieved in serum. Physical incompatibility and/or loss of activity of Flucloxacillin in solution has been reported when given with gentamycin sulphate, streptomycin sulphate, and vitamin mixtures.
- Flucloxacillin should not be added to intravenous lipids, blood products protein hydrolysates or other proteinaceous fluids.
USE IN PREGNANCY AND LACTATION
- The use of Flucloxacillin in pregnancy should be reserved for cases considered essential by the clinician. Use of the drug in the second and third trimesters may result in the sensitization of the fetus. During lactation, trace quantities of penicillin can be detected in breast milk.
STORAGE CONDITION
Store in a cool and dry place. Protect from light and moisture.
COMMERCIAL PACK
- Revistar 250 mg capsule: Each Box contains 7 x 4 capsules in an alu-alu blister pack.
- Revistar 500 mg capsule: Each Box containing 7 x 4 capsules in alu-alu blister pack.
- Revistar powder for suspension 100 ml: Each amber glass bottle containing dry powder for reconstitution to 100 ml suspension.
Biopharma Ltd. Produces REVISTAR 500 MG CAPSULE it is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.