OLVANCE ™
OLVANCE 20 MG TABLET | |
---|---|
Generic : | Olmesartan |
Thearapeutic : | Cardiovascular Drug |
Pack Size : | 30s |
Strength : | |
Dosage Form : | Tablet |
Olvance
Olmesartan Medoxomil BP 20 mg
PRESENTATION
- Olvance 20 mg Tablet: Each film-coated tablet contains Olmesartan Medoxomil BP 20 mg.
DESCRIPTION
- Olmesartan medoxomil is a selective angiotensin II receptor antagonist (AT1 subtype). Olmesartan medoxomil a prodrug, is hydrolyzed to olmesartan during absorption from the gastrointestinal tract.
USES
- For the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
DOSAGE & ADMINISTRATION
Dosage must be individualized. The usual recommended starting dose of Olmesartan is 20 mg once daily when used as monotherapy in patients who are not volume-contracted. For patients requiring further reduction in blood pressure after 2 weeks of therapy, the dose of Olmesartan may be increased to 40 mg. Doses above 40 mg do not appear to have a greater effect. Twice-daily dosing offers no advantage over the same total dose given once daily. No initial dosage adjustment is recommended for elderly patients, for patients with moderate to marked renal impairment (creatinine clearance < 40 ml/min), or with moderate to marked hepatic dysfunction. For patients with possible depletion of intravascular volume (e.g., patients treated with diuretics, particularly those with impaired renal function), Olmesartan should be initiated under close medical supervision and consideration should be given to the use of a lower starting dose. Olmesartan may be administered with or without food.
CONTRAINDICATION
- Olmesartan is contraindicated in patients who are hypersensitive to any component of this product.
SIDE EFFECTS
Treatment with Olmesartan was well tolerated, with an incidence of adverse events similar to placebo. The following adverse events occurred in placebo-controlled clinical trials at an incidence of more than 1% of patients treated with Olmesartan but also occurred at about the same or greater incidence in patients receiving placebo: back pain, bronchitis, creatine phosphokinase increased, diarrhea, headache, hematuria, hyperglycemia, hypertriglyceridemia, influenza-like symptoms, pharyngitis, rhinitis, and sinusitis.
USE IN PREGNANCY AND LACTATION
Pregnancy Categories: C (first trimester) and D (second and third trimesters).
Nursing Mothers: It is not known whether Olmesartan is excreted in human milk, but Olmesartan is secreted at low concentrations in the milk of lactating rats. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
PAEDIATRIC USE
- Safety and effectiveness in pediatric patients have not been established.
PRECAUTION
As a consequence of inhibiting the renin-angiotensin-aldosterone system, changes in renal function may be anticipated in susceptible individuals treated with olmesartan medoxomil. In patients whose renal function may depend upon the activity of the renin-angiotensin-aldosterone system (e.g. patients with severe congestive heart failure), treatment with angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists has been associated with oliguria and/or progressive azotemia and (rarely) with acute renal failure and/or death. Similar results may be anticipated in patients treated with olmesartan medoxomil.
STORAGE CONDITION
- Store in a cool and dry place, protect from light and moisture. Keep out of the reach of children.
COMMERCIAL PACK
- Olvance 20 mg Tablet: Each box contains 30 tablets in a blister pack.
Biopharma Ltd. Produces OLVANCE 20 MG TABLET it is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.