Lasocon D

Dexlansoprazole

Composition

• Lasocon D 30: Each capsule contains Dexlansoprazole INN 30 mg as enteric-coated pellets.

Description

Lasocon D (Dexlansoprazole) delayed-release capsule is a Proton Pump Inhibitor (PPI), that inhibits gastric acid secretion. Lasocon D (Dexlansoprazole) is the R-enantiomer of lansoprazole (A racemic mixture of the R- and S-enantiomers). Lasocon D (Dexlansoprazole) is supplied as a Dual Delayed Release (DDR) formulation in a capsule for oral administration. Lasocon D (Dexlansoprazole) capsule contains a mixture of two types of enteric-coated granules with different pH-dependent dissolution profiles.

Mechanism of Action

Lasocon D (Dexlansoprazole) is a PPI that suppresses gastric acid secretion by specific inhibition of the (H+/K+) ATPase in the gastric parietal cell. By acting specifically on the proton pump, Lasocon D (Dexlansoprazole) blocks the final step of acid production.

Pharmacokinetics

The formulation of Lasocon D (Dexlansoprazole) utilizing Dual Delayed Release technology results in a plasma concentration-time profile with two distinct peaks; the first peak occurs 1 to 2 hours after administration, followed by a second peak within 4 to 5 hours. No accumulation of Dexlansoprazole occurs after multiple once-daily doses of Lasocon D (Dexlansoprazole) 30 mg or 60 mg. After oral administration of Lasocon D (Dexlansoprazole) 30 mg or 60 mg to healthy subjects, mean Cmax and AUC values of Dexlansoprazole increased approximately dose proportionally. Dexlansoprazole is extensively metabolized in the liver and excreted by urine.

Indications

• Healing of Erosive Esophagitis: Lasocon D (Dexlansoprazole) is indicated for healing of all grades of Erosive Esophagitis (EE) for up to 8 weeks • Maintenance of Healed Erosive Esophagitis: Lasocon D (Dexlansoprazole) is indicated to maintain healing of EE and relief of heartburn for up to 6 months • Symptomatic Non-Erosive Gastroesophageal Reflux Disease: Lasocon D (Dexlansoprazole) is indicated for the treatment of heartburn associated with symptomatic Non-Erosive Gastroesophageal Reflux Disease (GERD) for 4 weeks.

Dosage and Administration

Biopharma Ltd. Produces LASOCON D 30MG CAPSULE it is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.